D-Threonine;
D-ALPHA-AMINO-BETA-HYDROXYBUTYRIC ACID;
D-2-AMINO-3-HYDROXYBUTANOIC ACID;
D-2-AMINO-3-HYDROXYBUTYRIC ACID;
D-Threonine;
(2R,3S)-2-Amino-3-hydroxybutyric acid;
D-α-Amino-β-hydroxybutyric acid;
(2R,3S)-(+)-Threonine;D-β-Hydroxy-2-aMinobutyric acid;
D-Threonine (D-2-AMino-3-hydroxybutanoic acid)
They are usually used to pack powder. And they can prevent sunshine and water from getting bad.
The hard carton can protect your products from crashing and getting wet.
D-Threonine (H-D-Thr-OH) is an enantiomer of L-threonine. D-Threonine is a metabolite of Saccharomyces cerevisiae.
Used in biochemical research.
Dl-threonine was used as raw material to react with chloroacetyl chloride under alkaline conditions. After decompression and concentration, the product was extracted by acetone. Finally, the product was separated by acylase.
Capriline is an auxin releasing peptide agonist used to treat insulin resistance in mammals.
Capromorelin Tartrate (CP 424391-18) is a growth hormone secretagogue (GHS). It is an agonist of ghrelin receptor and can be used as a novel therapy to stimulate appetite in dogs. The Ki value for hGHS-R1a was 7 nM, and the EC50 value for rat pituitary cells was 3 nM.
An inorganic or organic base (e.g. TEA, DMAP, hydroxide or carbonate, preferably TEA) is first added, followed by an amino protective group (preferably (Boc)2O) with 4-oxide-piperidin-3-ethyl formate hydrochloride in a reactive inert organic solvent (e.g. IPE, THF, dichloromethane and EtOAc in the presence or absence of water as a co-solvent. Preferably in a solution formed in IPE and water. Stir the mixture for approximately 1 to 24 hours, preferably overnight, and preferably under nitrogen. The organic phase is separated and post-processed according to a standard method known to technicians in the field, and then concentrated to obtain the desired product in crystalline form.
An inorganic or organic base (such as TEA, DMAP, hydroxide or carbonate, preferably lithium carbonate) is added to an organic solvent (e.g., THF, IPE, alcohol, DNF or DMSO, preferably DMF) of 4-oxide-piperidin-1, 3-dicarboxylate 1-tert-butyl 3-ethyl ester), and then benzyl bromide is added. Heat the mixture to approximately 25 to 100 ° C, preferably 60 ° C; And stir for approximately 1 to 24 hours, preferably 20 hours. The reaction mixture is then cooled to room temperature, extracted with an organic solvent (such as IPE, toluene, THF or EtOAc) and post-processed according to standard methods known to technicians in the field to obtain the required compounds.
At approximately 0 ° C to room temperature, methyl hydrazine is added to an organic solvent solution (e.g. alcohol, THF, or toluene) of 3-benzyl-4-oxide-piperidine-1, 3-diformate 1-tert-butyl 3-ethyl, followed by an acid (e.g. sulfuric acid, hydrochloric acid, acetic acid, or TsOH, preferably acetic acid). Heat the reaction mixture slowly to approximately 40 to 100℃, preferably about 65℃, and stir for approximately 3 to 10 hours, preferably about 7.5 hours. After cooling to room temperature, the organic layer is washed with 10% sodium hydrocarbonate, and post-processed and concentrated in accordance with the standard method known to technicians in the field to obtain the required compounds.
| Fmoc-L-Thr(tBu)-Phe-OH | Boc-L-Thr(me)-OH |
| H-L-Thr-OH | Boc-D-Thr-Ome |
| DL-Thr | Boc-D-Thr-OH |
| H-L-allo-Thr-OH | Boc-D-Thr(me)-OH |
| L-Thr(bzl) | Boc-D-Thr(Bzl)-OH |
| H-L-Thr(tBu)-OH | Cbz-Thr-OH |
| L-Thr(me) | Cbz-Thr-Obzl |
| Thr-Otbu.hcl | Z-L-Thr-ome |
| L-Thr(bzl).HCl | Cbz-D-Thr-OH |
| L-Thr(me).Hcl | Cbz-L-Thr(tBu)-OH |
| L-Thr-Obzl.HCl | Cbz-L-Thr(bzl)-OH |
| H-L-Thr-OMe.HCl | Cbz-L-Thr(tBu)-OH DCHA |
| L-Thr-Oet.Hcl | Fmoc-L-Thr-OH |
| L-Allo-Thr-Ome.Hcl | fmoc-L-Thr-OtBu |
| H-L-Thr-OBzl·oxalate | Fmoc-L-Thr-Obzl |
| D-Thr(bzl).HCl | Fmoc-L-Allo-Thr-OH |
| D-Thr-Oet.Hcl | Fmoc-Thr(tBu)-OH |
| D-Thr-Obzl.HCl | Fmoc-L-Thr(bzl)-OH |
| D-Thr-Ome.HCl | Fmoc-D-Thr-OH |
| DL-Thr-Ome.HCl | Fmoc-D-Thr(bzl)-OH |
| Boc-L-Thr-OtBu | Fmoc-D-Thr(tBu)-OH |
| Boc-L-Thr-OH | Fmoc-L-Thr(tBu)-Ser-OH |
| Boc-L-allo-Thr-OH | Boc-n-me-l-thr(bzl).CHA |
| Boc-Thr-OMe | Fmoc-N-Me-L-Thr(bzl)-OH |
| Boc-Thr-Obzl | Fmoc-L-Thr(tBu)-Gly-OH |
| Boc-L-Thr(tBu)-OH | (2S,3S)-2-Amino-3-methoxybutanoic acid/L-AlloThr(Me) |
| Boc-L-Thr(Bzl)-OH | (2S,3S)-2-Amino-3-methoxybutanoic acid/BOC-AlloThr(Me) |
| H-L-Thr(Bzl)-OBzl.oxalate |
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