Boc-O-Benzyl-L-threonine;
BOC-THR-OH;
BOC-THR(BZL)-OH;
Butoxacarbonylbenzylthreonine;
N-T-boc-O-benzyl-L-threonine*crystalline;
O-benzyl-N-tert-butoxycarbonyl-L-threonine;
N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-L-THREONINE;
NALPHA-tert-Butoxycarbonyl-O-benzyl-L-threonine
They are usually used to pack powder. And they can prevent sunshine and water from getting bad.
The hard carton can protect your products from crashing and getting wet.
White crystalline powder; Insoluble in water and petroleum ether, soluble in ethyl acetate and methanol; mp is 115-116℃; Specific rotation [α]20D+15.8°(0.5-2.0 mg/ml, methanol).
Used for polypeptide synthesis, as an amino acid protection monomer.
O-benzyl-l-threonine was suspended in dioxane solution and acylated with tert-butylcarbonyl azide to obtain a crude product, which was extracted by ethyl acetate at pH of 9-10 and then recrystallized.
An active part of thymic oietin Ⅱ of thymus secretions. Thymoietin II is a single polypeptide compound isolated from thymus hormone. It is composed of 49 amino acids, and the peptide chain fragment composed of 5 amino acids has all the same physiological functions as thymoietin II. Therefore, this pentapeptide fragment is called thymus pentapeptide. White freeze-dried loose mass or powder.
One of the roles of thymus pentapeptide is to induce T cell differentiation. It can selectively induce the transformation of Thy-1- prothorax cells into Thy-1+ T cells. T cell differentiation is mediated by increased intracellular cAMP levels. Another basic function of thymus pentapeptides is to bind to specific receptors of mature peripheral blood T cells, increase intracellular cAMP level, and thus induce a series of intracellular reactions, which is also the basis of its immunomodulatory function. In normal body condition, thymus pentapeptide showed immune stimulating effect, which could significantly increase the E rosette formation rate and conversion rate of splenic lymphocytes, enhance the different stages of the primary or secondary immune response, and increase the number of IgM type and IgG or IgA type antibody forming cells. Thymus pentapeptide can also enhance the phagocytosis function of macrophages, increase the enzyme and phagocytosis function of polymorphonuclear neutrophils, increase the circulating antibody content, and enhance the immune function of red blood cells. Thymus pentapeptide can activate CD4 and CD8 positive cells, so that specific Tc cells can maintain longer life, but also can activate Th cells and induce the function of Ts cells. The antiinfectious and therapeutic effects of thymus pentapeptide are related to its enhancement of TC cell activity. An appropriate amount of thymus pentapeptide can significantly increase the production of interferon in anti-infection immunity. Inducing and promoting T cell differentiation and maturation; CD4/CD8 tended to be normal by regulating the proportion of T lymphocyte subsets; Enhance the phagocytosis function of macrophages; Enhance red blood cell immune function; Increase the activity of natural killer cells; Increase the level of interleukin-2 production and receptor expression; Enhance the production of γ interferon in peripheral blood mononuclear cells; Enhance SOD activity in serum.
It can be used in malignant tumor patients with immune function impairment after radiotherapy and chemotherapy. Treatment of hepatitis B; Major surgical operations and severe infections; Autoimmune diseases such as rheumatoid arthritis, lupus erythematosus; Type II diabetes mellitus, menopause syndrome; A person with weakened immune function.
| Fmoc-L-Thr(tBu)-Phe-OH | Boc-D-Thr-OH |
| H-L-Thr-OH | Boc-D-Thr(me)-OH |
| DL-Thr | Boc-D-Thr(Bzl)-OH |
| H-L-allo-Thr-OH | Cbz-Thr-OH |
| L-Thr(bzl) | Cbz-Thr-Obzl |
| H-L-Thr(tBu)-OH | Z-L-Thr-ome |
| L-Thr(me) | Cbz-D-Thr-OH |
| Thr-Otbu.hcl | Cbz-L-Thr(tBu)-OH |
| L-Thr(bzl).HCl | Cbz-L-Thr(bzl)-OH |
| L-Thr(me).Hcl | Cbz-L-Thr(tBu)-OH DCHA |
| L-Thr-Obzl.HCl | Fmoc-L-Thr-OH |
| H-L-Thr-OMe.HCl | fmoc-L-Thr-OtBu |
| L-Thr-Oet.Hcl | Fmoc-L-Thr-Obzl |
| L-Allo-Thr-Ome.Hcl | Fmoc-L-Allo-Thr-OH |
| H-L-Thr-OBzl·oxalate | Fmoc-Thr(tBu)-OH |
| D-Thr(bzl).HCl | Fmoc-L-Thr(bzl)-OH |
| D-Thr-Oet.Hcl | Fmoc-D-Thr-OH |
| D-Thr-Obzl.HCl | Fmoc-D-Thr(bzl)-OH |
| D-Thr-Ome.HCl | Fmoc-D-Thr(tBu)-OH |
| DL-Thr-Ome.HCl | Fmoc-L-Thr(tBu)-Ser-OH |
| Boc-L-Thr-OtBu | Boc-n-me-l-thr(bzl).CHA |
| Boc-L-Thr-OH | Fmoc-N-Me-L-Thr(bzl)-OH |
| Boc-L-allo-Thr-OH | Fmoc-L-Thr(tBu)-Gly-OH |
| Boc-Thr-OMe | (2S,3S)-2-Amino-3-methoxybutanoic acid/L-AlloThr(Me) |
| Boc-Thr-Obzl | (2S,3S)-2-Amino-3-methoxybutanoic acid/BOC-AlloThr(Me) |
| Boc-L-Thr(tBu)-OH | H-L-Thr(Bzl)-OBzl.oxalate |
| Boc-L-Thr(Bzl)-OH | Boc-D-Thr-Ome |
| Boc-L-Thr(me)-OH |
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